Presidents converge to salute one of their own

DALLAS (AP) ? All the living American presidents past and present are gathering in Dallas, a rare reunion to salute one of their own at the dedication of the George W. Bush Presidential Center.

Profound ideological differences and a bitter history of blaming each other for the nation's woes will give way ? if just for a day ? to pomp and pleasantries Thursday as the five members of the most exclusive club in the world appear publicly together for the first time in years. For Bush, 66, the ceremony also marks his unofficial return to the public eye four years after the end of his deeply polarizing presidency.

On the sprawling, 23-acre university campus north of downtown Dallas housing his presidential library, museum and policy institute, Bush will be feted by his father, George H.W. Bush, and the two surviving Democrats, Bill Clinton and Jimmy Carter. President Barack Obama, fresh off a fundraiser for Democrats the night before, will also speak.

In a reminder of his duties as the current Oval Office inhabitant, Obama will travel to Waco in the afternoon for a memorial for victims of last week's deadly fertilizer plant explosion.

Key moments and themes from Bush's presidency ? the harrowing, the controversial and the inspiring ? won't be far removed from the minds of the presidents and guests assembled to dedicate the center, where interactive exhibits invite scrutiny of Bush's major choices as president, such as the financial bailout, the Iraq War and the international focus on HIV and AIDS.

On display is the bullhorn that Bush, near the start of his presidency, used to punctuate the chaos at ground zero three days after 9/11. Addressing a crowd of rescue workers amid the ruins of the World Trade Center, Bush said: "I can hear you. The rest of the world hears you. And the people who knocked these buildings down will hear all of us soon."

"Memories are fading rapidly, and the profound impact of that attack is becoming dim with time," Bush told The Associated Press earlier this month. "We want to make sure people remember not only the lives lost and the courage shown, but the lesson that the human condition overseas matters to the national security of our country."

More than 70 million pages of paper records. Two hundred million emails. Four million digital photos. About 43,000 artifacts. Bush's library will feature the largest digital holdings of any of the 13 presidential libraries under the auspices of the National Archives and Records Administration, officials said. Situated in a 15-acre urban park at Southern Methodist University, the center includes 226,000 square feet of indoor space.

A full-scale replica of the Oval Office as it looked during Bush's tenure sits on the campus, as does a piece of steel from the World Trade Center. In the museum, visitors can gaze at a container of chads ? the remnants of the famous Florida punch card ballots that played a pivotal role in the contested 2000 election that sent Bush to Washington.

Former first lady Laura Bush led the design committee, officials said, with a keen eye toward ensuring that her family's Texas roots were conspicuously reflected. Architects used local materials, including Texas Cordova cream limestone and trees from the central part of the state, in its construction.

The public look back on the tenure of the nation's 43rd president comes as Bush is undergoing a coming-out of sorts after years spent in relative seclusion, away from the prying eyes of cameras and reporters that characterized his two terms in the White House and his years in the Texas governor's mansion before that. As the library's opening approached, Bush and his wife embarked on a round-robin of interviews with all the major television networks, likely aware that history's appraisal of his legacy and years in office will soon be solidifying.

An erroneous conclusion that Iraq had weapons of mass destruction, a bungling of the federal government's response to Hurricane Katrina and a national debt that grew much larger under his watch stain the memory of his presidency for many, including Obama, who won two terms in the White House after lambasting the choices of its previous resident. But on Wednesday, Obama staunchly defended Bush's commitment to the America's well-being while addressing Democratic donors.

"Whatever our political differences, President Bush loves this country and loves his people and shared that same concern, and is concerned about all people in America," Obama said. "Not just some. Not just those who voted Republican."

There's at least some evidence that Americans are warming to Bush's presidency four years after he returned to his ranch in Crawford, even if they still question his judgment on Iraq and other issues. While Bush left office with an approval rating of 33 percent, that figure has climbed to 47 percent ? about equal to Obama's own approval rating, according to a Washington Post-ABC News poll released ahead of the library opening.

Bush pushed forcefully but unsuccessfully for the type of sweeping immigration overhaul that Congress, with Obama's blessing, is now pursuing. And his aggressive approach to counterterrorism may be viewed with different eyes as the U.S. continues to be touched by acts of terrorism.

Although museums and libraries, by their nature, look back on history, the dedication of Bush's library also offers a few hints about the future, with much of the nation's top political brass gathered in the same state. Clinton's wife, Hillary Rodham Clinton, stoked speculation about her own political future Wednesday in a Dallas suburb when she delivered her first paid speech since stepping down as secretary of state earlier this year. And Bush talked up the presidential prospects of his brother, former Florida Gov. Jeb Bush, in an interview that aired Wednesday on ABC.

"He doesn't need my counsel, because he knows what it is, which is, 'Run,'" Bush said.

Obama, too, may have his own legacy in mind. He's just a few years out from making his own decision about where to house his presidential library and the monument to his legacy.

___

Follow Josh Lederman on Twitter: http://twitter.com/joshledermanAP

Source: http://news.yahoo.com/presidents-converge-salute-one-own-065629221--politics.html

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A risk including gay partners in immigration bill?

WASHINGTON (AP) ? Frustrated at being left out of an immigration overhaul, gay rights groups are pushing to adjust a bipartisan Senate bill to include gay couples. But Democrats are treading carefully, wary of adding another divisive issue that could lose Republican support and jeopardize the entire bill.

Both parties want the bill to succeed. Merely getting to agreement on the basic framework for the immigration overhaul, which would create a long and costly path to citizenship for the estimated 11 million people in the U.S. illegally, was no small feat for senators. And getting it through a divided Congress is still far from a done deal.

Even so, gay rights groups, their lobbyists and grass-roots supporters are insisting the deal shouldn't exclude bi-national, same-sex couples ? about 28,500 of them, according to a 2011 study from the Williams Institute at UCLA Law. They're ramping up a campaign to change the bill to allow gay Americans to sponsor their partners for green cards, the same way straight Americans can. Supporters trekked to the Capitol to make their case at senators' offices on Wednesday.

"Opponents will be proposing amendments that, if passed, could collapse this very fragile coalition that we've been able to achieve," Sen. John McCain, an Arizona Republican, said last week at the unveiling of the bill. He said the eight senators from both parties who crafted the legislation are committed to voting against changes that could kill it.

For Democrats, it's a precarious position to be in. Democratic senators overwhelmingly support gay marriage ? all but three are now on the record voicing their support ? and two dozen of them this year backed a separate bill called the Uniting American Families Act to let gays sponsor their partners independent of a comprehensive immigration overhaul.

But the party's senators are still bruised from an agonizing defeat on gun control this month. And few seem eager to inject divisive issues that might sink their best prospects for a major legislative victory this year and a potential keystone of President Barack Obama's legacy.

"Any amendment which might sink the immigration bill, I would worry about," Sen. Carl Levin, D-Mich., said in a brief interview, adding that he had yet to decide whether an amendment for gays and lesbians would meet that yardstick.

Support from both Hispanics and gays was critical to Obama's re-election, and his overwhelming advantage among Hispanics was a major factor prompting Republicans to warm to immigration overhaul almost immediately after. But now, one community's gain on the immigration front could be to the other's detriment.

"As you continue to add other issues to the immigration discussion, it's going to make it more challenging," said Sen. John Hoeven, a North Dakota Republican.

Patrick Leahy, D-Vt., who chairs the Senate Judiciary Committee, has committed to offering an amendment to the bill to allow gay citizens to sponsor their partners, said Ty Cobb, an attorney and lobbyist with the Human Rights Campaign, a gay rights group. Another Democratic senator, Al Franken of Minnesota, pledged in a Judiciary hearing on the bill Monday to do "everything we can" to adjust the bill.

But even if the amendment makes it through the Senate, it faces a tougher path if and when the bill moves to the Republican-controlled House. GOP leaders there have been defending the Defense of Marriage Act, which defines marriage as between a man and a woman, though Obama has said it is unconstitutional. And while Obama supports same-sex marriage, his administration has shown little appetite for forcing the issue while the immigration overhaul's prospects are still shaky.

"No one will get everything they want from it, including the president. That's the nature of compromise. But the bill is largely consistent with the principles he has laid out repeatedly," Obama spokesman Jay Carney said last week. A White House spokesman declined to answer further questions about the issue.

Some Democrats argue privately that with the Supreme Court poised to rule on the constitutionality of the Defense of Marriage Act, which prohibits the government from giving federal marriage benefits to gay couples, the issue could soon be moot. Still, even if the high court strikes the law down, it would only bring partial relief; only couples married in the nine states that recognize gay marriages would probably be eligible.

The issue has generated an intense advocacy campaign, with gay rights organizations and Hispanic groups such as the National Council of La Raza squaring off with religious interests such as the U.S. Conference of Catholic Bishops, which sent a letter to Obama telling him including the provision could jeopardize the whole bill.

At the Human Rights Campaign, four of its seven federal lobbyists are engaged in pushing lawmakers to back such an amendment. Immigration Equality, another group supporting the provision, said it was bringing more than 60 families from 24 states to the Capitol on Wednesday to ask lawmakers to offer their support.

And Log Cabin Republicans, a gay conservative group, is making a pro-business pitch with potential GOP supporters, arguing that including gay couples would allow U.S. companies to retain the best talent instead of forcing good workers to leave the U.S. to be with their partners.

Such may be the case for Paul Coyle, a 45-year-old partner in a Chicago law firm, who has spent the past 10 years in a long-distance relationship with his partner in Toronto. At first, the two men would take turns flying back and forth, he said, until immigration officials cracked down, making it harder for his partner to enter the U.S. Now Coyle flies to Canada every other week, wondering each time whether it would be cheaper and more rewarding to pack up his law practice and move to Canada.

"It's emotionally draining. It's financially draining, and every time he comes to the U.S., there's the risk he won't get let back in," Coyle said. "But when you're in love, you just take the risk, because it's worth it."

___

Follow Josh Lederman on Twitter: http://twitter.com/joshledermanAP

Source: http://news.yahoo.com/risk-including-gay-partners-immigration-bill-180537783--politics.html

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[Drunk Music Reviews] SXSW Travelogue: Part IV - Each Note Secure

Drunk Music Reviews?is exactly what it sounds like: Caitlin Behle reviews shows while progressively getting drunker, while illustrator?John Sebastian?turns the drunken reviews, which could be ridiculous, sloppy or just plain insulting, into a comic.

?

Part of the charm of SXSW is the people-watching. Austin?s motto is ?Keep Austin Weird? and they ain?t shitting you. There are some lovely characters floating around, and like a kid in a candy shop, John wanted to draw all of them. As John put it, ?There were a lot of real life caricatures there, it was really hard to not want to draw everybody.?

A sampling (with notes by John):

Nasty Canasta

?Nasty Canasta? is a dude working the door at some bar next to Mugshots.?He had a cut off shirt and shoulder hair, and looked like he needed a head tattoo of a sailboat to be riding the sea of head fat.

(Author?s note: Mugshots is?an oasis of dirt cheap whiskey with a shady patio. It?s a welcome break from live music if you just need to hang out and get drunk in the quiet of your own shame.).

Junkie Chic

Some girl I saw. She kind of represented the typical SXSW-ian you?d run into there.

?

(Author?s Note: Other typical SXSW-ians included Overdressed Hipsters, Confused But Delighted Broes, and for some reason, Topless Ladies Riding Pedicabs.)

Shitty Tommy Lee

Shitty Tommy Lee was some guy in spandex animal print pants, hat, and boa, a leather vest, lots of guyliner, and a mesh tank top. He was stuck in LA in 1986 and looked coked out of his fucking mind.

The Melting Girl

We saw The Melting Girl outside of The Russian Room.?She was named as such because it looked like her face was melting.

The Pinstripes Sketcher

Meta-DMR sketching! This nerd was drawing The Pinstripes while they were busking on 6th street. His illustrations weren?t great.

?

About Caitlin Behle

Caitlin has been with Each Note Secure since her days at WOXY as an evening DJ beginning in 2008. As a senior contributor with ENS, most of her live reviews are centered on Cincinnati's local music scene. She also provides the words for Drunk Music Reviews, a series of reviews written in collaboration with illustrator John Sebastian in which they both get hammered and write/draw their live concert experiences.

Source: http://www.eachnotesecure.com/drunk-music-reviews-sxsw-travelogue-part-iv/

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Bayern tops AP rankings for 4th straight week

MANCHESTER, England (AP) ? It's turning into a procession for Bayern Munich in the Associated Press global soccer poll.

For the fourth straight week, the German champions were voted the top team by a panel of journalists following back-to-back 6-1 wins ? first against Wolfsburg in the German Cup semifinals and then over Hannover on Saturday for its 13th straight Bundesliga victory.

"As much as I like Barcelona, boy is it tough not to like the way Bayern Munich is playing right now," said Tom Timmermann, of the St. Louis Post-Dispatch. "Two 6-1 wins in one week? I don't care who you're playing. I like to see that."

There was more good news for Germany with national team playmaker Mesut Oezil voted the best player of the week thanks to his double for Real Madrid in a 3-1 home win over Real Betis.

Oezil's silky display at the Santiago Bernabeu overshadowed that of international colleague Mario Gomez, whose five goals last week earned him a share of second place with Tottenham forward Gareth Bale.

The showy display of scoring last week included Robin van Persie, whose hat trick in a 3-0 win over Aston Villa secured Manchester United a 20th English title. But it landed him only seventh in the player voting.

Whether Bayern stays at the head of the line or is toppled by Barcelona could hinge on the outcome of Tuesday's Champions League semifinal first leg between two of Europe's heavyweight clubs.

"The best German title-winning side ever?" Will Tidey, of the Bleacher Report, asked of Bayern. "The argument is being made and you can see why based on Bayern's depth and their dominance this season."

Nine of the 17 voters gave Bayern top marks, leaving Jupp Heynckes' side 30 points ahead of second-place Juventus in the poll.

Gomez and fellow striker Claudio Pizarro have been scoring in recent weeks for Bayern and both made the top six.

"There's a Mario Gomez song button you can press every time he scores," Tidey added. "It's been pressed five times in the past week."

Juve is closing in on the Italian title and can have Arturo Vidal to thank for pressing home the team's advantage this week. The midfielder from Chile scored both goals in a 2-0 win over Lazio on Monday before landing the winner over AC Milan on Sunday. Two of those goals came from the penalty spot.

"I'm not really big on rewarding him for someone else's work in drawing the foul," Timmermann said. "Still, we've seen enough players botch penalty kicks to know they're not quite gimmies."

Bale's return from an ankle injury inspired Tottenham to a 3-1 win against Manchester City and he was rewarded with 81 points from the panel. Tottenham was third among the teams.

"Tottenham may not be a one-man team, but they are a completely different proposition when Gareth Bale is in the side," said Julian Bennetts, of the Hayters News Agency in England.

Luis Suarez may have finished higher had he not attempted to take a chunk out of Branislav Ivanovic's arm in Liverpool's 2-2 draw with Chelsea. The Uruguay striker set up Daniel Sturridge's tying goal and scored himself in the final minute of injury time to earn 30 points and ninth place in the players list ? but by that time he had been caught on video biting Ivanovic.

It may be the last time we see Suarez in the AP poll for a while.

"Luis Suarez does not make it onto my list as his conduct when he appears to bite Branislav Ivanovic outweighs the impact he made in creating a goal and scoring the equalizer that earned a point," said Mike McGrath, of Wardles News Agency and The Sun.

____

AP Global Soccer Rankings for the week ending April 22.

Based on 17 voters, using 10 points for first, nine for second, one for bottom place. Previous rankings in parentheses.

Teams:

1. Bayern Munich (1), 141 points.

2. Juventus, 111.

3. Tottenham, 87.

4. Real Madrid (3), 71.

5. Barcelona (4), 67.

tie. Manchester United (6), 67.

7. Paris Saint-Germain (7), 58.

8. Borussia Dortmund (2), 55.

9. Valencia, 50.

10. Arsenal, 21.

Players:

1. Mesut Oezil, 95 points.

2. Gareth Bale, 81.

(tie) Mario Gomez, 81.

4. Robert Lewandowski (6) 47.

5. Roberto Soldado, 45.

(tie) Arturo Vidal, 45.

7. Robin van Persie (10), 38.

8. Radamel Falcao (5), 33.

9. Luis Suarez, 30.

10. Daniel Sturridge, 29.

Source: http://news.yahoo.com/bayern-tops-ap-rankings-4th-straight-week-135518728--sow.html

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House GOP report: Hillary Clinton lied under oath about additional Benghazi security request (Michellemalkin)

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Top legal adviser to Egypt's president resigns

CAIRO (AP) ? The legal adviser of Egypt's Islamist President Mohammed Morsi resigned Tuesday, alleging that the Muslim Brotherhood has monopolized decision-making and encroached on the governing of the country.

The resignation letter by Mohammed Fouad Gadallah brought the harshest criticism yet from inside the presidency. Opponents of Morsi have long accused the Brotherhood of being the real power behind the president and say the group's attempts to dominate power have fueled the country's turmoil.

Morsi, who hails from the Brotherhood, denied in a TV interview earlier this week that the group intervenes in decision-making.

The resignation comes amid a mounting dispute between Morsi's Islamist supporters and the judiciary, which is the sole branch of government not dominated by Islamists.

Brotherhood officials and other Islamists accuse backers of the regime of ousted autocrat Hosni Mubarak in the courts of blocking the country's transition to democracy and are discussing a law they say will ensure the judicary's independence. But opponents fear they aim to take over the courts and purge secular-minded judges to consolidate Brotherhood power.

Two days earlier, Justice Minister Ahmed Mekki, an Islamist supporter, submitted his resignation, complaining that Morsi supporters were "trampling" on the judiciary. He too criticized the president's handling of the dispute with the judiciary and failure to reach out to critics.

The opposition and judges threatened to escalate their fight against the new legislation, while Morsi said he doesn't accept any encroachment on the judiciary.

Gadallah, who is not a member of the Muslim Brotherhood, served as Morsi's legal adviser since July. Presidential spokesman Ihab Fahmy confirmed that the resignation was submitted and said it was under review. He offered no other details. An email to the presidency seeking further comment was not answered.

In his three-page resignation letter, Gadallah said he wanted to shed light "on the extent of the danger facing the country," at a time when "personal interests are overwhelming national interests."

He said there is "no clear vision" in running state affairs and that "a single (political) current" monopolizes decision-making, excluding experts and the opposition. He also pointed to the current dispute over the courts, complaining of attempts to "assassinate the judiciary."

He said he had long been concerned over "the slowness of decision-making and monopolization by the Brotherhood and its encroachment on the president and governing." But he said that he had previously held back from resigning or going public with his objections out of respect for Morsi.

Gadallah said he advised Morsi against some of a series of controversial decrees the president issued in November that sparked a heavy public backlash and galvanized the opposition.

Particularly, he said he opposed a decree that temporarily granted Morsi's decisions immunity from judicial review, but he said his opinion was ignored. After the public outcry, some Brotherhood members had blamed Gadallah for those decrees.

Brotherhood spokesman Yasser Mehrez dismissed Gadallah's claims of the group dominating rule, telling the online version of Al-Ahram newspaper, "it seems (he) has been influenced by what the opposition says about Brotherhoodization."

Mehrez also said the envisioned law on the judiciary was in line with demands many, including Gadallah, have made for reform, contending that judges who protected the Mubarak regime are leading the resistance to the new law.

Gamal Heshmat, a lawmaker from the Brotherhood's Freedom and Justice Party, said the group appreciates Gadallah's opinion on legal matters the presidency consults him on. "But he should only stick to what he knows," Heshmat said.

Egypt has been deeply divided for months over Morsi's rule and the political dominance of his Islamist allies, leading to repeated violence even as the country's economy continues to deteriorate.

In a quick reaction to Gadallah's resignation, opposition leader Mohammed ElBaradei said he held Morsi and his supporters responsible for the polarization that is tearing the country apart.

"Egypt is a train wreck waiting to happen," ElBaradei wrote on his Twitter account. "Polarization (is) at dangerous level; Morsi's aides (are) jumping ship. National reconciliation (is) crucial."

Islamists have pointed to a number of recent cases in which Mubarak-era officials have been cleared of charges as evidence of the need to reform the judiciary.

On Tuesday, a court convicted a former finance minister, Yousef Boutros-Ghali, on charges of squandering around $3.6 million during his final years in his post. The court sentenced him to 25 years in prison. Boutros-Ghali, a nephew of former U.N. Secretary-General Boutros Boutros-Ghali, is believed to be in London.

Because he has been tried in absentia, he is allowed a retrial and all verdicts can be overturned upon his return.

___

Amir Makar contributed to this report.

Source: http://news.yahoo.com/top-legal-adviser-egypts-president-resigns-175758759.html

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'Toggle switch' to burn fat identified

Apr. 23, 2013 ? For a long time, scientists have dreamt of converting undesirable white fat cells into brown fat cells and thus simply have excess pounds melt away. Researchers at the University of Bonn have now gotten a step closer to this goal: They decoded a "toggle switch" in mice which can significantly stimulate fat burning.

The results are now being presented in the journal Nature Communications.

Many people not only in industrialized nations struggle with excess weight -- but all fat is not alike. "Love handles" in particular contain troublesome white fat cells which store excess food. Brown fat cells are the exact opposite: they burn excess energy as the desirable "heaters" of the body. Scientists at the University of Bonn working with Prof. Dr. Alexander Pfeifer, Director of the Institute for Pharmacology and Toxicology, have spent years using animal models to explore how the undesirable white fat can be converted into sought-after brown fat. "In this way, excess pounds may be able to simply be melted away and obesity combated," says Prof. Pfeifer.

A kind of "trigger switch" spurs fat burning

The researchers have now decoded a "microRNA switch" in mice which is important for brown fat cells. Micro-RNAs are located in the genome of cells and very quickly and efficiently regulate gene activity. The researchers studied a specific microRNA: microRNA 155. The gene regulator micro-RNA 155 inhibits a certain transcription factor, that controls brown fat cell function. Surprisingly, Prof. Pfeifer and his team found that the transcription factor also regulates the levels microRNA 155 establishing a tight feed-back loop that works like a toggle switch: When the microRNA is highly expressed brown fat cell differentiation is blocked; conversely, if the transcription factor wins the upper hand, brown fat is produced at an increased level and this in turn boosts fat burning in the body.

In knockout mice, the gene for Micro-RNA 155 was silent

The researchers at Bonn University and their colleagues from the Federal Institute of Drugs and Medical Devices (BfArM) and from the University of Regensburg worked with so-called transgenic and knockout mice in whom the gene for micro-RNA 155 was either increased or silenced. "The mechanism was already set in motion when the micro-RNA 155 was only halved in the mice," reports lead author Yong Chen, graduate student of the NRW International Graduate School BIOTECH-PHARMA. The mice then had significantly more brown fat cells available than did the control gro up -- and had even converted white fat cells into brown fat cells.

Clues to the causes of lipid metabolism diseases

The micro-RNA functions as an antagonist to the brown fat cells. "As long as enough micro-RNA 155 is present, the production of brown fat cells is blocked," says Chen. Only if it falls below a certain proportion does this brake let up; the blueprint for brown fat can be read and implemented by the cell -- the desired fat burners can develop. These findings help scientists better understand the causes of lipid metabolism diseases.

Hope for new therapies against obesity

The scientists at the University of Bonn see in their results a potential starting point for drugs to combat obesity. The researchers have clues to the fact that the results, if anything, can be transferred from mice to humans. Thus, for example, researchers in Leipzig found increased levels of micro-RNA 155 in significantly overweight patients. This corresponds to findings from animal models: A lot of micro-RNA 155 is associated with reduced fat burning. "However, we are still in the basic research stage," says Prof. Pfeifer. The path to suitable drugs is still a long one.

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The above story is reprinted from materials provided by Universit?t Bonn, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Yong Chen, Franziska Siegel, Stefanie Kipschull, Bodo Haas, Holger Fr?hlich, Gunter Meister, Alexander Pfeifer. miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit. Nature Communications, 2013; 4: 1769 DOI: 10.1038/ncomms2742

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/2asP3gl0lPk/130423110742.htm

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